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True B12 toxicity symptoms are rare but may include skin reactions such as acne-like eruptions, mild gastrointestinal disturbances, and occasional headaches, particularly following injections

People allergic to cobalt or cobalamin, those with Lebers hereditary optic neuropathy , and those with severe hypersensitivity should be careful with B12 supplements

Vitamin B12 Deficiency and Its Implications Causes of Deficiency Vitamin B12 deficiency can occur due to various reasons, including inadequate dietary intake, malabsorption issues, certain medical conditions, and the use of specific medications